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aminocaproic acid การใช้

ประโยคมือถือ
  • First-line options include the antifibrinolytics tranexamic acid or aminocaproic acid.
  • They covalently attached polyamidoamine ( PAMAM ) dendrimers with aminocaproic acid spacers to a silicon oxide surface.
  • Tranexamic acid and aminocaproic acid inhibit fibrinolysis, and lead to a " de facto " reduced bleeding rate.
  • Antifibrinolytics, such as aminocaproic acid ( ?-aminocaproic acid ) and tranexamic acid are used as inhibitors of fibrinolysis.
  • Antifibrinolytics, such as aminocaproic acid ( ?-aminocaproic acid ) and tranexamic acid are used as inhibitors of fibrinolysis.
  • Tranexamic and aminocaproic acids inhibit the conversion of plasminogen to plasmin, plasmin being the agent of fibrin breakdown in blood clots.
  • Aminocaproic acid is also an intermediate in the polymerization of Nylon-6, where it is formed by ring-opening hydrolysis of caprolactam.
  • Two studies published in early 2008, both comparing aprotinin with aminocaproic acid, found that mortality was increased by 32 and 64 %, respectively.
  • Epsilon-aminocaproic acid could be used to treat hereditary C1-INH deficiency, though the possible side effect of intravascular thrombosis should be weighed.
  • The preliminary findings suggest that, compared to other antifibrinolytic drugs ( epsilon-aminocaproic acid and tranexamic acid ) aprotinin may increase the risk of death.
  • Finally, U of Florida has found good results with two different medications used in combination : aminocaproic acid ( EACA ) and n-acetylcysteine ( NAC ).
  • Since the use of aprotinin has been abandoned due to major side effects, the treatment or prophylaxis of hyperfibrinolysis is made with synthetic drugs such as tranexamic acid, epsilon-aminocaproic acid or other lysine analogues.
  • Carothers surmised that the problem with the polyamides that had been made from ?-aminocaproic acid was due to cyclization reactions, so he replaced ?-aminocaproic acid with 9-aminononoic acid which would not cyclize.
  • Carothers surmised that the problem with the polyamides that had been made from ?-aminocaproic acid was due to cyclization reactions, so he replaced ?-aminocaproic acid with 9-aminononoic acid which would not cyclize.